I try to respond to all of the messages I receive, especially well-crafted emails that get to the point quickly. If it takes me a few minutes to respond, I will. If your message requires a complex or multi-faceted response, you probably won't hear back from me. (Looking for my paid services?)
Before pitching a guest post
Check the guest post archives to get an idea of what type of guests and guest posts I typically accept. I rarely accept guest posts from people or businesses outside of the writing and publishing community. My standards are high, and I sometimes ask for revisions. If you want help on pitching a guest post, try this advice from Copyblogger, or this advice from Problogger. Both methods are acceptable.
Many people mistakenly think I'm a literary agent or publisher, but I'm not. I cannot publish your work, nor can I personally match you with a publisher. However, I've written a comprehensive post on how you can find an agent or publisher.